Assay Detail
Functional
CHEMBL1613915
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor. (Class of assay: confirmatory) [Related pubchem assays: 856, 736 ]
82
Total Activities
81
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Category | confirmatory |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 82 | 5.45 | 6.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1518905 | — | — | 1 | 6.23 |
| CHEMBL1504701 | — | — | 1 | 6.17 |
| CHEMBL533602 | — | — | 1 | 6.04 |
| CHEMBL1574879 | — | — | 1 | 6.03 |
| CHEMBL1309450 | — | — | 1 | 6.01 |
| CHEMBL1344225 | — | — | 1 | 6.01 |
| CHEMBL1334062 | — | — | 1 | 6.00 |
| CHEMBL1563943 | — | — | 1 | 5.91 |
| CHEMBL601757 | — | — | 1 | 5.85 |
| CHEMBL1309232 | — | — | 1 | 5.83 |
| CHEMBL1432251 | — | — | 1 | 5.78 |
| CHEMBL1369655 | — | — | 1 | 5.75 |
| CHEMBL1447924 | — | — | 2 | 5.69 |
| CHEMBL1470979 | — | — | 1 | 5.61 |
| CHEMBL1566928 | — | — | 1 | 5.60 |
| CHEMBL1343392 | — | — | 1 | 5.58 |
| CHEMBL1540682 | — | — | 1 | 5.55 |
| CHEMBL1481347 | — | — | 1 | 5.53 |
| CHEMBL1404792 | — | — | 1 | 5.53 |
| CHEMBL1465527 | — | — | 1 | 5.51 |
| CHEMBL576409 | — | — | 1 | 5.51 |
| CHEMBL1543839 | — | — | 1 | 5.50 |
| CHEMBL1322078 | — | — | 1 | 5.48 |
| CHEMBL1881714 | — | — | 1 | 5.47 |
| CHEMBL1531073 | — | — | 1 | 5.46 |
| CHEMBL1393783 | — | — | 1 | 5.46 |
| CHEMBL1347469 | — | — | 1 | 5.44 |
| CHEMBL1413625 | — | — | 1 | 5.43 |
| CHEMBL1417204 | — | — | 1 | 5.43 |
| CHEMBL1986259 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1518905 | — | IC50 | = | 587.0 | nM | 6.23 |
| CHEMBL1504701 | — | IC50 | = | 682.0 | nM | 6.17 |
| CHEMBL533602 | — | IC50 | = | 922.0 | nM | 6.04 |
| CHEMBL1574879 | — | IC50 | = | 942.0 | nM | 6.03 |
| CHEMBL1309450 | — | IC50 | = | 977.0 | nM | 6.01 |
| CHEMBL1344225 | — | IC50 | = | 967.0 | nM | 6.01 |
| CHEMBL1334062 | — | IC50 | = | 996.0 | nM | 6.00 |
| CHEMBL1563943 | — | IC50 | = | 1230.0 | nM | 5.91 |
| CHEMBL601757 | — | IC50 | = | 1402.0 | nM | 5.85 |
| CHEMBL1309232 | — | IC50 | = | 1484.0 | nM | 5.83 |
| CHEMBL1432251 | — | IC50 | = | 1675.0 | nM | 5.78 |
| CHEMBL1369655 | — | IC50 | = | 1759.0 | nM | 5.75 |
| CHEMBL1447924 | — | IC50 | = | 2063.0 | nM | 5.69 |
| CHEMBL1470979 | — | IC50 | = | 2467.0 | nM | 5.61 |
| CHEMBL1566928 | — | IC50 | = | 2530.0 | nM | 5.60 |
| CHEMBL1343392 | — | IC50 | = | 2652.0 | nM | 5.58 |
| CHEMBL1447924 | — | IC50 | = | 2730.0 | nM | 5.56 |
| CHEMBL1540682 | — | IC50 | = | 2789.0 | nM | 5.55 |
| CHEMBL1481347 | — | IC50 | = | 2943.0 | nM | 5.53 |
| CHEMBL1404792 | — | IC50 | = | 2939.0 | nM | 5.53 |
| CHEMBL576409 | — | IC50 | = | 3104.0 | nM | 5.51 |
| CHEMBL1465527 | — | IC50 | = | 3072.0 | nM | 5.51 |
| CHEMBL1543839 | — | IC50 | = | 3153.0 | nM | 5.50 |
| CHEMBL1322078 | — | IC50 | = | 3308.0 | nM | 5.48 |
| CHEMBL1881714 | — | IC50 | = | 3357.0 | nM | 5.47 |
| CHEMBL1531073 | — | IC50 | = | 3471.0 | nM | 5.46 |
| CHEMBL1393783 | — | IC50 | = | 3445.0 | nM | 5.46 |
| CHEMBL1347469 | — | IC50 | = | 3627.0 | nM | 5.44 |
| CHEMBL1413625 | — | IC50 | = | 3674.0 | nM | 5.43 |
| CHEMBL1417204 | — | IC50 | = | 3688.0 | nM | 5.43 |
| CHEMBL1986259 | — | IC50 | = | 3710.0 | nM | 5.43 |
| CHEMBL1565349 | — | IC50 | = | 3808.0 | nM | 5.42 |
| CHEMBL1341270 | — | IC50 | = | 3792.0 | nM | 5.42 |
| CHEMBL1572967 | — | IC50 | = | 3765.0 | nM | 5.42 |
| CHEMBL1465592 | — | IC50 | = | 3798.0 | nM | 5.42 |
| CHEMBL1411912 | — | IC50 | = | 3769.0 | nM | 5.42 |
| CHEMBL1304582 | — | IC50 | = | 3905.0 | nM | 5.41 |
| CHEMBL1496004 | — | IC50 | = | 4014.0 | nM | 5.40 |
| CHEMBL1546374 | — | IC50 | = | 4278.0 | nM | 5.37 |
| CHEMBL3196976 | — | IC50 | = | 4326.0 | nM | 5.36 |
| CHEMBL1428153 | — | IC50 | = | 4374.0 | nM | 5.36 |
| CHEMBL1422386 | — | IC50 | = | 4393.0 | nM | 5.36 |
| CHEMBL1467961 | — | IC50 | = | 4503.0 | nM | 5.35 |
| CHEMBL1563483 | — | IC50 | = | 4499.0 | nM | 5.35 |
| CHEMBL1424968 | — | IC50 | = | 4674.0 | nM | 5.33 |
| CHEMBL1535539 | — | IC50 | = | 4684.0 | nM | 5.33 |
| CHEMBL1607568 | — | IC50 | = | 4770.0 | nM | 5.32 |
| CHEMBL1304169 | — | IC50 | = | 5088.0 | nM | 5.29 |
| CHEMBL1420175 | — | IC50 | = | 5199.0 | nM | 5.28 |
| CHEMBL3199050 | — | IC50 | = | 5975.0 | nM | 5.22 |