Compound Detail
CHEMBL1563483
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Basic Information
| ChEMBL ID | CHEMBL1563483 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AWAPBXGSDGWNHK-OXAWKVHCSA-N |
9
Targets
16
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
294.4
MW (Da)
2.44
ALogP
4
HBA
0
HBD
68.3
PSA (Ų)
0.61
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 13 meas. best 6.14
EC50 3 meas. best 5.78
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.14 | 5.35 | 720.0 | 6 |
| Sphingosine 1-phosphate receptor 4 CHEMBL3230 | IC50 | 5.89 | 5.89 | 1276.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.78 | 5.78 | 1678.0 | 1 |
| Sphingosine 1-phosphate receptor 2 CHEMBL2955 | IC50 | 5.71 | 5.53 | 1964.0 | 2 |
| DNA damage-inducible transcript 3 protein CHEMBL2146304 | IC50 | 5.67 | 5.67 | 2120.0 | 1 |
| X-box-binding protein 1 CHEMBL1741176 | IC50 | 5.57 | 5.57 | 2680.0 | 1 |
| Heat shock factor protein 1 CHEMBL5313 | EC50 | 5.52 | 5.52 | 3038.0 | 1 |
| Type-1 angiotensin II receptor CHEMBL227 | IC50 | 5.43 | 5.43 | 3673.0 | 1 |
| Large ribosomal subunit protein eL19A CHEMBL1741172 | EC50 | 4.9 | 4.9 | 12480.0 | 1 |
| Sphingosine 1-phosphate receptor 1 CHEMBL4333 | IC50 | 4.86 | 4.86 | 13690.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine