Assay Detail
Functional
CHEMBL1963746
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MAPK9
934
Total Activities
916
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | other |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 934 | 6.22 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL244378 | — | — | 1 | 8.80 |
| CHEMBL396523 | — | — | 1 | 8.60 |
| CHEMBL378627 | — | — | 1 | 8.50 |
| CHEMBL210618 | — | — | 1 | 8.40 |
| CHEMBL377408 | — | — | 1 | 8.40 |
| CHEMBL243088 | — | — | 1 | 8.40 |
| CHEMBL242865 | — | — | 1 | 8.30 |
| CHEMBL1987034 | — | — | 1 | 8.20 |
| CHEMBL2001957 | — | — | 1 | 8.20 |
| CHEMBL2006581 | — | — | 1 | 8.20 |
| CHEMBL103667 | DORAMAPIMOD | 2.0 | 1 | 8.20 |
| CHEMBL2000429 | — | — | 1 | 8.20 |
| CHEMBL210963 | — | — | 1 | 8.20 |
| CHEMBL2004355 | — | — | 1 | 8.20 |
| CHEMBL210928 | — | — | 1 | 8.00 |
| CHEMBL1090356 | — | — | 1 | 8.00 |
| CHEMBL377383 | — | — | 1 | 8.00 |
| CHEMBL1991429 | — | — | 1 | 7.90 |
| CHEMBL424872 | — | — | 1 | 7.90 |
| CHEMBL1995832 | — | — | 1 | 7.90 |
| CHEMBL1965423 | — | — | 1 | 7.80 |
| CHEMBL1241473 | — | — | 1 | 7.80 |
| CHEMBL437747 | — | — | 1 | 7.70 |
| CHEMBL209534 | — | — | 1 | 7.70 |
| CHEMBL2003657 | — | — | 1 | 7.70 |
| CHEMBL1986781 | — | — | 1 | 7.70 |
| CHEMBL1982563 | — | — | 1 | 7.60 |
| CHEMBL1090360 | — | — | 1 | 7.60 |
| CHEMBL1230122 | R-1487 | 1.0 | 1 | 7.60 |
| CHEMBL1982874 | — | — | 1 | 7.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL244378 | — | Ki | = | 1.585 | nM | 8.80 |
| CHEMBL396523 | — | Ki | = | 2.512 | nM | 8.60 |
| CHEMBL378627 | — | Ki | = | 3.162 | nM | 8.50 |
| CHEMBL243088 | — | Ki | = | 3.981 | nM | 8.40 |
| CHEMBL377408 | — | Ki | = | 3.981 | nM | 8.40 |
| CHEMBL210618 | — | Ki | = | 3.981 | nM | 8.40 |
| CHEMBL242865 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL210963 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL2001957 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL2004355 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL103667 | DORAMAPIMOD | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL2000429 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL1987034 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL2006581 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL210928 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1090356 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL377383 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL424872 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1991429 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1995832 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1241473 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1965423 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL437747 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1986781 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL2003657 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL209534 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1982874 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1230122 | R-1487 | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1090360 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1982563 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL2004419 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1991800 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL458997 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1984842 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1991678 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1990288 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1983715 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1988163 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1984206 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1994040 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1990904 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1991395 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1725279 | SP-600125 | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL2000408 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1984700 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1990288 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1969735 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1971186 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL475251 | R-406 | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL482967 | CYC-116 | Ki | = | 79.43 | nM | 7.10 |