Compound Detail
CHEMBL2004355
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Basic Information
| ChEMBL ID | CHEMBL2004355 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IYHNFVWLUSPIBF-UHFFFAOYSA-N |
10
Targets
10
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
375.4
MW (Da)
0.51
ALogP
7
HBA
3
HBD
161.2
PSA (Ų)
0.66
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 10 meas. best 8.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 8.2 | 8.2 | 6.3 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Mitogen-activated protein kinase 1 CHEMBL4040 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| RAC-alpha serine/threonine-protein kinase CHEMBL4282 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine