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Assay Detail

CHEMBL1963707

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PRKD2
ChEMBL ↗
749
Total Activities
739
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Serine/threonine-protein kinase D2 (CHEMBL4900) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 749 5.90 8.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1980995 — — 1 8.60
CHEMBL1990496 — — 1 8.20
CHEMBL437747 — — 1 8.10
CHEMBL1997129 — — 1 8.10
CHEMBL1986263 — — 1 7.90
CHEMBL1982874 — — 1 7.90
CHEMBL2001751 — — 1 7.80
CHEMBL302449 GO-6976 — 1 7.80
CHEMBL1986943 — — 2 7.70
CHEMBL1965423 — — 1 7.70
CHEMBL1966628 — — 1 7.60
CHEMBL2003657 — — 1 7.60
CHEMBL1970903 — — 1 7.50
CHEMBL1967878 CENISERTIB 2.0 1 7.50
CHEMBL1991063 — — 1 7.50
CHEMBL244378 — — 1 7.40
CHEMBL226403 — — 1 7.40
CHEMBL1974870 — — 1 7.40
CHEMBL592030 — — 1 7.30
CHEMBL509032 TAE-684 — 1 7.30
CHEMBL1973540 — — 1 7.30
CHEMBL396523 — — 1 7.30
CHEMBL2004419 — — 1 7.30
CHEMBL1983111 — — 1 7.20
CHEMBL1987034 — — 1 7.10
CHEMBL1971186 — — 1 7.10
CHEMBL1982957 — — 1 7.10
CHEMBL340384 — — 1 7.10
CHEMBL1997617 — — 1 7.10
CHEMBL1993661 — — 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1980995 — Ki = 2.512 nM 8.60
CHEMBL1990496 — Ki = 6.31 nM 8.20
CHEMBL1997129 — Ki = 7.943 nM 8.10
CHEMBL437747 — Ki = 7.943 nM 8.10
CHEMBL1982874 — Ki = 12.59 nM 7.90
CHEMBL1986263 — Ki = 12.59 nM 7.90
CHEMBL302449 GO-6976 Ki = 15.85 nM 7.80
CHEMBL2001751 — Ki = 15.85 nM 7.80
CHEMBL1965423 — Ki = 19.95 nM 7.70
CHEMBL1986943 — Ki = 19.95 nM 7.70
CHEMBL1986943 — Ki = 19.95 nM 7.70
CHEMBL1966628 — Ki = 25.12 nM 7.60
CHEMBL2003657 — Ki = 25.12 nM 7.60
CHEMBL1991063 — Ki = 31.62 nM 7.50
CHEMBL1970903 — Ki = 31.62 nM 7.50
CHEMBL1967878 CENISERTIB Ki = 31.62 nM 7.50
CHEMBL226403 — Ki = 39.81 nM 7.40
CHEMBL244378 — Ki = 39.81 nM 7.40
CHEMBL1974870 — Ki = 39.81 nM 7.40
CHEMBL396523 — Ki = 50.12 nM 7.30
CHEMBL509032 TAE-684 Ki = 50.12 nM 7.30
CHEMBL592030 — Ki = 50.12 nM 7.30
CHEMBL1973540 — Ki = 50.12 nM 7.30
CHEMBL2004419 — Ki = 50.12 nM 7.30
CHEMBL1983111 — Ki = 63.1 nM 7.20
CHEMBL1987034 — Ki = 79.43 nM 7.10
CHEMBL1997617 — Ki = 79.43 nM 7.10
CHEMBL1982957 — Ki = 79.43 nM 7.10
CHEMBL1971186 — Ki = 79.43 nM 7.10
CHEMBL340384 — Ki = 79.43 nM 7.10
CHEMBL1993661 — Ki = 100.0 nM 7.00
CHEMBL1190711 — Ki = 125.89 nM 6.90
CHEMBL1974328 — Ki = 125.89 nM 6.90
CHEMBL2005475 — Ki = 125.89 nM 6.90
CHEMBL243088 — Ki = 125.89 nM 6.90
CHEMBL1977681 — Ki = 125.89 nM 6.90
CHEMBL1969523 — Ki = 125.89 nM 6.90
CHEMBL1981725 — Ki = 125.89 nM 6.90
CHEMBL1725279 SP-600125 Ki = 158.49 nM 6.80
CHEMBL1965836 — Ki = 158.49 nM 6.80
CHEMBL1971029 — Ki = 158.49 nM 6.80
CHEMBL2006439 — Ki = 199.53 nM 6.70
CHEMBL2001239 — Ki = 199.53 nM 6.70
CHEMBL1978448 — Ki = 199.53 nM 6.70
CHEMBL1968590 — Ki = 199.53 nM 6.70
CHEMBL1988163 — Ki = 199.53 nM 6.70
CHEMBL1967094 — Ki = 199.53 nM 6.70
CHEMBL1969588 — Ki = 251.19 nM 6.60
CHEMBL1982711 — Ki = 251.19 nM 6.60
CHEMBL226471 — Ki = 251.19 nM 6.60