Compound Detail
CHEMBL1971186
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1971186 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MGNQNQOSSLCUFP-UHFFFAOYSA-N |
19
Targets
19
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
378.4
MW (Da)
3.35
ALogP
7
HBA
2
HBD
80.3
PSA (Ų)
0.57
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 19 meas. best 7.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Casein kinase I isoform alpha CHEMBL2793 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Casein kinase I isoform gamma-3 CHEMBL5084 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| ALK tyrosine kinase receptor CHEMBL4247 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Casein kinase I isoform gamma-1 CHEMBL2426 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Casein kinase I isoform gamma-2 CHEMBL2543 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase pim-2 CHEMBL4523 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Mitogen-activated protein kinase 1 CHEMBL4040 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine