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Assay Detail

CHEMBL1963686

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CSNK1G2
ChEMBL ↗
605
Total Activities
595
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Casein kinase I isoform gamma-2 (CHEMBL2543) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 605 5.94 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2003638 — — 1 8.40
CHEMBL1997129 — — 1 8.40
CHEMBL1991078 — — 1 8.20
CHEMBL1969588 — — 1 8.20
CHEMBL1999931 — — 1 8.10
CHEMBL1977223 — — 1 7.70
CHEMBL1965660 — — 2 7.60
CHEMBL1996066 — — 1 7.60
CHEMBL1989646 — — 1 7.50
CHEMBL1965631 — — 1 7.50
CHEMBL1981079 — — 1 7.40
CHEMBL2006439 — — 1 7.40
CHEMBL1994830 — — 1 7.40
CHEMBL396523 — — 1 7.30
CHEMBL1992937 — — 1 7.30
CHEMBL1964290 — — 1 7.20
CHEMBL1969523 — — 1 7.20
CHEMBL225519 — — 1 7.20
CHEMBL1986263 — — 1 7.20
CHEMBL1974870 — — 1 7.10
CHEMBL243088 — — 1 7.10
CHEMBL244378 — — 1 7.00
CHEMBL1969843 — — 1 7.00
CHEMBL1975128 — — 1 6.90
CHEMBL1991063 — — 1 6.90
CHEMBL1966628 — — 1 6.80
CHEMBL1998159 — — 1 6.80
CHEMBL1964692 — — 1 6.80
CHEMBL226471 — — 1 6.80
CHEMBL1988153 — — 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1997129 — Ki = 3.981 nM 8.40
CHEMBL2003638 — Ki = 3.981 nM 8.40
CHEMBL1969588 — Ki = 6.31 nM 8.20
CHEMBL1991078 — Ki = 6.31 nM 8.20
CHEMBL1999931 — Ki = 7.943 nM 8.10
CHEMBL1977223 — Ki = 19.95 nM 7.70
CHEMBL1965660 — Ki = 25.12 nM 7.60
CHEMBL1965660 — Ki = 25.12 nM 7.60
CHEMBL1996066 — Ki = 25.12 nM 7.60
CHEMBL1989646 — Ki = 31.62 nM 7.50
CHEMBL1965631 — Ki = 31.62 nM 7.50
CHEMBL1981079 — Ki = 39.81 nM 7.40
CHEMBL2006439 — Ki = 39.81 nM 7.40
CHEMBL1994830 — Ki = 39.81 nM 7.40
CHEMBL396523 — Ki = 50.12 nM 7.30
CHEMBL1992937 — Ki = 50.12 nM 7.30
CHEMBL225519 — Ki = 63.1 nM 7.20
CHEMBL1964290 — Ki = 63.1 nM 7.20
CHEMBL1969523 — Ki = 63.1 nM 7.20
CHEMBL1986263 — Ki = 63.1 nM 7.20
CHEMBL243088 — Ki = 79.43 nM 7.10
CHEMBL1974870 — Ki = 79.43 nM 7.10
CHEMBL244378 — Ki = 100.0 nM 7.00
CHEMBL1969843 — Ki = 100.0 nM 7.00
CHEMBL1975128 — Ki = 125.89 nM 6.90
CHEMBL1991063 — Ki = 125.89 nM 6.90
CHEMBL1966628 — Ki = 158.49 nM 6.80
CHEMBL1998159 — Ki = 158.49 nM 6.80
CHEMBL1964692 — Ki = 158.49 nM 6.80
CHEMBL226471 — Ki = 158.49 nM 6.80
CHEMBL1988153 — Ki = 199.53 nM 6.70
CHEMBL1990288 — Ki = 251.19 nM 6.60
CHEMBL210887 — Ki = 251.19 nM 6.60
CHEMBL116070 — Ki = 251.19 nM 6.60
CHEMBL1965836 — Ki = 251.19 nM 6.60
CHEMBL1978014 — Ki = 251.19 nM 6.60
CHEMBL1975900 — Ki = 251.19 nM 6.60
CHEMBL1967878 CENISERTIB Ki = 251.19 nM 6.60
CHEMBL2002479 — Ki = 316.23 nM 6.50
CHEMBL340384 — Ki = 316.23 nM 6.50
CHEMBL2002726 — Ki = 316.23 nM 6.50
CHEMBL226403 — Ki = 316.23 nM 6.50
CHEMBL1987034 — Ki = 316.23 nM 6.50
CHEMBL1995813 — Ki = 398.11 nM 6.40
CHEMBL497151 — Ki = 398.11 nM 6.40
CHEMBL404367 — Ki = 398.11 nM 6.40
CHEMBL2000354 — Ki = 398.11 nM 6.40
CHEMBL1988163 — Ki = 398.11 nM 6.40
CHEMBL1988300 — Ki = 398.11 nM 6.40
CHEMBL482967 CYC-116 Ki = 501.19 nM 6.30