Compound Detail
CHEMBL1978014
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Basic Information
| ChEMBL ID | CHEMBL1978014 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HWGZXYUOXGVACR-UHFFFAOYSA-N |
12
Targets
12
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
415.5
MW (Da)
2.91
ALogP
8
HBA
1
HBD
94.9
PSA (Ų)
0.55
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 12 meas. best 7.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Casein kinase I isoform gamma-2 CHEMBL2543 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Casein kinase I isoform gamma-1 CHEMBL2426 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Casein kinase I isoform gamma-3 CHEMBL5084 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| cGMP-dependent protein kinase 1 CHEMBL4273 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 CHEMBL4575 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Mitogen-activated protein kinase 1 CHEMBL4040 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Serine/threonine-protein kinase Sgk2 CHEMBL5794 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine