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Assay Detail

CHEMBL1964100

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: TOPK
ChEMBL ↗
584
Total Activities
579
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Lymphokine-activated killer T-cell-originated protein kinase (CHEMBL4896) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 584 5.63 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1974328 — — 1 8.00
CHEMBL1973098 — — 1 6.90
CHEMBL1966722 — — 1 6.70
CHEMBL1989646 — — 1 6.60
CHEMBL1974803 — — 1 6.50
CHEMBL583144 — — 1 6.50
CHEMBL1991800 — — 1 6.50
CHEMBL2003271 — — 1 6.40
CHEMBL1966343 — — 1 6.40
CHEMBL1988173 — — 1 6.40
CHEMBL1990482 — — 1 6.40
CHEMBL1976455 — — 1 6.40
CHEMBL1974935 — — 1 6.30
CHEMBL2001751 — — 1 6.30
CHEMBL225519 — — 1 6.30
CHEMBL1965131 — — 1 6.30
CHEMBL1973142 — — 1 6.30
CHEMBL1966628 — — 1 6.20
CHEMBL1995813 — — 1 6.20
CHEMBL1986263 — — 1 6.20
CHEMBL1974310 — — 1 6.20
CHEMBL1982711 — — 1 6.20
CHEMBL1998611 — — 1 6.10
CHEMBL2000832 — — 1 6.10
CHEMBL2000393 — — 1 6.10
CHEMBL1725279 SP-600125 — 1 6.00
CHEMBL1970903 — — 1 6.00
CHEMBL2006263 — — 1 5.90
CHEMBL1984274 — — 1 5.90
CHEMBL1969537 — — 1 5.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1974328 — Ki = 10.0 nM 8.00
CHEMBL1973098 — Ki = 125.89 nM 6.90
CHEMBL1966722 — Ki = 199.53 nM 6.70
CHEMBL1989646 — Ki = 251.19 nM 6.60
CHEMBL1974803 — Ki = 316.23 nM 6.50
CHEMBL1991800 — Ki = 316.23 nM 6.50
CHEMBL583144 — Ki = 316.23 nM 6.50
CHEMBL1990482 — Ki = 398.11 nM 6.40
CHEMBL1976455 — Ki = 398.11 nM 6.40
CHEMBL2003271 — Ki = 398.11 nM 6.40
CHEMBL1966343 — Ki = 398.11 nM 6.40
CHEMBL1988173 — Ki = 398.11 nM 6.40
CHEMBL1965131 — Ki = 501.19 nM 6.30
CHEMBL2001751 — Ki = 501.19 nM 6.30
CHEMBL1973142 — Ki = 501.19 nM 6.30
CHEMBL1974935 — Ki = 501.19 nM 6.30
CHEMBL225519 — Ki = 501.19 nM 6.30
CHEMBL1974310 — Ki = 630.96 nM 6.20
CHEMBL1982711 — Ki = 630.96 nM 6.20
CHEMBL1986263 — Ki = 630.96 nM 6.20
CHEMBL1966628 — Ki = 630.96 nM 6.20
CHEMBL1995813 — Ki = 630.96 nM 6.20
CHEMBL2000832 — Ki = 794.33 nM 6.10
CHEMBL2000393 — Ki = 794.33 nM 6.10
CHEMBL1998611 — Ki = 794.33 nM 6.10
CHEMBL1725279 SP-600125 Ki = 1000.0 nM 6.00
CHEMBL1970903 — Ki = 1000.0 nM 6.00
CHEMBL2006263 — Ki = 1258.93 nM 5.90
CHEMBL1984274 — Ki = 1258.93 nM 5.90
CHEMBL1969537 — Ki = 1258.93 nM 5.90
CHEMBL2002726 — Ki = 1258.93 nM 5.90
CHEMBL1975500 — Ki = 1584.89 nM 5.80
CHEMBL1975138 — Ki = 1584.89 nM 5.80
CHEMBL1995740 — Ki = 1584.89 nM 5.80
CHEMBL1964687 — Ki = 1584.89 nM 5.80
CHEMBL1190711 — Ki = 1584.89 nM 5.80
CHEMBL1992634 — Ki = 1584.89 nM 5.80
CHEMBL1964444 — Ki = 1995.26 nM 5.70
CHEMBL2004447 — Ki = 1995.26 nM 5.70
CHEMBL396523 — Ki = 1995.26 nM 5.70
CHEMBL1969506 — Ki = 1995.26 nM 5.70
CHEMBL1990635 — Ki = 1995.26 nM 5.70
CHEMBL1997349 — Ki = 1995.26 nM 5.70
CHEMBL1978448 — Ki = 1995.26 nM 5.70
CHEMBL592030 — Ki = 2511.89 nM 5.60
CHEMBL1974870 — Ki = 2511.89 nM 5.60
CHEMBL1993584 — Ki = 2511.89 nM 5.60
CHEMBL2005528 — Ki = 2511.89 nM 5.60
CHEMBL1970522 — Ki = 2511.89 nM 5.60
CHEMBL2000354 — Ki = 2511.89 nM 5.60