Compound Detail
CHEMBL1964444
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1964444 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YEKVTSRZMPLPFK-UHFFFAOYSA-N |
22
Targets
22
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
346.3
MW (Da)
4.60
ALogP
3
HBA
2
HBD
66.9
PSA (Ų)
0.71
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 22 meas. best 7.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Tyrosine-protein kinase FRK CHEMBL4223 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Cyclin-dependent kinase 8 CHEMBL5719 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Homeodomain-interacting protein kinase 4 CHEMBL1075167 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Casein kinase II subunit alpha CHEMBL3629 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Activin receptor type-1 CHEMBL5903 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Serine/threonine-protein kinase pim-3 CHEMBL5407 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Protein-tyrosine kinase 6 CHEMBL4601 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 CHEMBL4852 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Lymphokine-activated killer T-cell-originated protein kinase CHEMBL4896 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Macrophage-stimulating protein receptor CHEMBL2689 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Protein kinase C gamma type CHEMBL2938 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine