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Assay Detail

CHEMBL1963735

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CSNK2A1
ChEMBL ↗
746
Total Activities
734
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Casein kinase II subunit alpha (CHEMBL3629) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 746 6.13 8.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1999931 — — 1 8.50
CHEMBL1987034 — — 1 8.40
CHEMBL2003286 — — 1 8.40
CHEMBL1241473 — — 1 8.40
CHEMBL2002407 — — 1 8.30
CHEMBL2003638 — — 1 8.20
CHEMBL1969264 — — 1 8.20
CHEMBL244378 — — 1 8.00
CHEMBL1991078 — — 1 7.80
CHEMBL1978448 — — 1 7.80
CHEMBL2000354 — — 1 7.70
CHEMBL526133 — — 1 7.60
CHEMBL396523 — — 1 7.60
CHEMBL1970522 — — 1 7.50
CHEMBL1994538 — — 1 7.40
CHEMBL475251 R-406 2.0 1 7.40
CHEMBL1988163 — — 1 7.40
CHEMBL1980540 — — 1 7.30
CHEMBL1974702 — — 1 7.30
CHEMBL1972119 — — 1 7.30
CHEMBL1989856 — — 1 7.20
CHEMBL1972937 — — 1 7.20
CHEMBL1996066 — — 1 7.20
CHEMBL539474 — — 1 7.10
CHEMBL1966816 — — 1 7.10
CHEMBL1969537 — — 1 7.10
CHEMBL243088 — — 1 7.10
CHEMBL2005186 BELUMOSUDIL 4.0 1 7.00
CHEMBL458997 — — 1 7.00
CHEMBL1966808 — — 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1999931 — Ki = 3.162 nM 8.50
CHEMBL1987034 — Ki = 3.981 nM 8.40
CHEMBL1241473 — Ki = 3.981 nM 8.40
CHEMBL2003286 — Ki = 3.981 nM 8.40
CHEMBL2002407 — Ki = 5.012 nM 8.30
CHEMBL2003638 — Ki = 6.31 nM 8.20
CHEMBL1969264 — Ki = 6.31 nM 8.20
CHEMBL244378 — Ki = 10.0 nM 8.00
CHEMBL1978448 — Ki = 15.85 nM 7.80
CHEMBL1991078 — Ki = 15.85 nM 7.80
CHEMBL2000354 — Ki = 19.95 nM 7.70
CHEMBL396523 — Ki = 25.12 nM 7.60
CHEMBL526133 — Ki = 25.12 nM 7.60
CHEMBL1970522 — Ki = 31.62 nM 7.50
CHEMBL475251 R-406 Ki = 39.81 nM 7.40
CHEMBL1988163 — Ki = 39.81 nM 7.40
CHEMBL1994538 — Ki = 39.81 nM 7.40
CHEMBL1972119 — Ki = 50.12 nM 7.30
CHEMBL1980540 — Ki = 50.12 nM 7.30
CHEMBL1974702 — Ki = 50.12 nM 7.30
CHEMBL1996066 — Ki = 63.1 nM 7.20
CHEMBL1989856 — Ki = 63.1 nM 7.20
CHEMBL1972937 — Ki = 63.1 nM 7.20
CHEMBL1969537 — Ki = 79.43 nM 7.10
CHEMBL243088 — Ki = 79.43 nM 7.10
CHEMBL539474 — Ki = 79.43 nM 7.10
CHEMBL1966816 — Ki = 79.43 nM 7.10
CHEMBL497151 — Ki = 100.0 nM 7.00
CHEMBL2005186 BELUMOSUDIL Ki = 100.0 nM 7.00
CHEMBL458997 — Ki = 100.0 nM 7.00
CHEMBL1966808 — Ki = 100.0 nM 7.00
CHEMBL592030 — Ki = 100.0 nM 7.00
CHEMBL1991674 — Ki = 100.0 nM 7.00
CHEMBL482967 CYC-116 Ki = 125.89 nM 6.90
CHEMBL560813 — Ki = 125.89 nM 6.90
CHEMBL583144 — Ki = 125.89 nM 6.90
CHEMBL1993661 — Ki = 125.89 nM 6.90
CHEMBL1968151 — Ki = 125.89 nM 6.90
CHEMBL1986943 — Ki = 158.49 nM 6.80
CHEMBL474432 — Ki = 158.49 nM 6.80
CHEMBL1991434 — Ki = 158.49 nM 6.80
CHEMBL1682553 — Ki = 158.49 nM 6.80
CHEMBL1976455 — Ki = 158.49 nM 6.80
CHEMBL1986943 — Ki = 158.49 nM 6.80
CHEMBL1965660 — Ki = 199.53 nM 6.70
CHEMBL1965660 — Ki = 199.53 nM 6.70
CHEMBL1975128 — Ki = 251.19 nM 6.60
CHEMBL1964444 — Ki = 251.19 nM 6.60
CHEMBL1973711 — Ki = 251.19 nM 6.60
CHEMBL1997846 — Ki = 251.19 nM 6.60