Compound Detail
CHEMBL1989856
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1989856 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UPITUWGOTMBQLX-UHFFFAOYSA-N |
25
Targets
25
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
251.2
MW (Da)
2.19
ALogP
5
HBA
1
HBD
78.4
PSA (Ų)
0.67
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 25 meas. best 7.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Casein kinase II subunit alpha CHEMBL3629 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Tyrosine-protein kinase JAK3 CHEMBL2148 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Tyrosine-protein kinase ITK/TSK CHEMBL2959 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase PLK3 CHEMBL4897 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase PLK1 CHEMBL3024 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine