Compound Detail
CHEMBL2002407
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Basic Information
| ChEMBL ID | CHEMBL2002407 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WCAKSXQRFBVWDG-UHFFFAOYSA-N |
25
Targets
25
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
281.3
MW (Da)
1.64
ALogP
6
HBA
3
HBD
131.7
PSA (Ų)
0.73
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 25 meas. best 8.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Casein kinase II subunit alpha CHEMBL3629 | Ki | 8.3 | 8.3 | 5.0 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Serine/threonine-protein kinase pim-2 CHEMBL4523 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 CHEMBL3553 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Tyrosine-protein kinase JAK3 CHEMBL2148 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine