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Assay Detail

CHEMBL1964111

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CAMK2A
ChEMBL ↗
343
Total Activities
331
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Calcium/calmodulin-dependent protein kinase type II subunit alpha (CHEMBL4147) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 343 5.54 8.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1980995 — — 1 8.50
CHEMBL1988581 — — 1 7.40
CHEMBL1980407 — — 1 7.20
CHEMBL1986943 — — 2 6.80
CHEMBL2002099 — — 2 6.80
CHEMBL1990885 — — 1 6.80
CHEMBL1988141 — — 1 6.80
CHEMBL1973720 — — 2 6.70
CHEMBL1973359 — — 1 6.70
CHEMBL1977138 — — 1 6.60
CHEMBL2007421 — — 1 6.50
CHEMBL1991078 — — 1 6.40
CHEMBL1981133 — — 1 6.40
CHEMBL1969151 — — 1 6.40
CHEMBL1996510 — — 1 6.30
CHEMBL1991734 — — 1 6.30
CHEMBL509032 TAE-684 — 1 6.20
CHEMBL1993661 — — 1 6.20
CHEMBL1982711 — — 1 6.10
CHEMBL1972346 — — 1 6.10
CHEMBL2000029 — — 1 6.00
CHEMBL2004025 — — 1 6.00
CHEMBL1972355 — — 1 6.00
CHEMBL1975903 — — 1 6.00
CHEMBL1983980 — — 1 6.00
CHEMBL2002723 — — 1 5.90
CHEMBL1996702 — — 1 5.80
CHEMBL1995211 — — 1 5.80
CHEMBL1997193 — — 1 5.80
CHEMBL1978166 — — 2 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1980995 — Ki = 3.162 nM 8.50
CHEMBL1988581 — Ki = 39.81 nM 7.40
CHEMBL1980407 — Ki = 63.1 nM 7.20
CHEMBL1986943 — Ki = 158.49 nM 6.80
CHEMBL1990885 — Ki = 158.49 nM 6.80
CHEMBL2002099 — Ki = 158.49 nM 6.80
CHEMBL1988141 — Ki = 158.49 nM 6.80
CHEMBL1986943 — Ki = 158.49 nM 6.80
CHEMBL1973720 — Ki = 199.53 nM 6.70
CHEMBL1973720 — Ki = 199.53 nM 6.70
CHEMBL1973359 — Ki = 199.53 nM 6.70
CHEMBL1977138 — Ki = 251.19 nM 6.60
CHEMBL2007421 — Ki = 316.23 nM 6.50
CHEMBL2002099 — Ki = 316.23 nM 6.50
CHEMBL1991078 — Ki = 398.11 nM 6.40
CHEMBL1981133 — Ki = 398.11 nM 6.40
CHEMBL1969151 — Ki = 398.11 nM 6.40
CHEMBL1996510 — Ki = 501.19 nM 6.30
CHEMBL1991734 — Ki = 501.19 nM 6.30
CHEMBL509032 TAE-684 Ki = 630.96 nM 6.20
CHEMBL1993661 — Ki = 630.96 nM 6.20
CHEMBL1972346 — Ki = 794.33 nM 6.10
CHEMBL1982711 — Ki = 794.33 nM 6.10
CHEMBL2004025 — Ki = 1000.0 nM 6.00
CHEMBL1972355 — Ki = 1000.0 nM 6.00
CHEMBL2000029 — Ki = 1000.0 nM 6.00
CHEMBL1983980 — Ki = 1000.0 nM 6.00
CHEMBL1975903 — Ki = 1000.0 nM 6.00
CHEMBL2002723 — Ki = 1258.93 nM 5.90
CHEMBL1996702 — Ki = 1584.89 nM 5.80
CHEMBL1997193 — Ki = 1584.89 nM 5.80
CHEMBL1978166 — Ki = 1584.89 nM 5.80
CHEMBL1983575 — Ki = 1584.89 nM 5.80
CHEMBL1978166 — Ki = 1584.89 nM 5.80
CHEMBL1995211 — Ki = 1584.89 nM 5.80
CHEMBL1980167 — Ki = 1995.26 nM 5.70
CHEMBL1967878 CENISERTIB Ki = 1995.26 nM 5.70
CHEMBL1998953 — Ki = 1995.26 nM 5.70
CHEMBL1974480 — Ki = 1995.26 nM 5.70
CHEMBL2007574 — Ki = 1995.26 nM 5.70
CHEMBL1983715 — Ki = 1995.26 nM 5.70
CHEMBL1992073 — Ki = 2511.89 nM 5.60
CHEMBL1940137 — Ki = 2511.89 nM 5.60
CHEMBL1993335 — Ki = 2511.89 nM 5.60
CHEMBL1980329 — Ki = 2511.89 nM 5.60
CHEMBL565612 SOTRASTAURIN Ki = 3162.28 nM 5.50
CHEMBL1983111 — Ki = 3162.28 nM 5.50
CHEMBL2006439 — Ki = 3162.28 nM 5.50
CHEMBL1996646 — Ki = 3162.28 nM 5.50
CHEMBL1982413 — Ki = 3162.28 nM 5.50