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Assay Detail

CHEMBL3050175

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Phytotoxicity against Allium cepa (onion) assessed as growth inhibition of root length measured 7 days post treatment
ChEMBL ↗
19
Total Activities
15
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Allium cepa
Confidence 1 — Organism
Curated By Autocuration

Target

Allium cepa (CHEMBL613790) ↗
Type ORGANISM
Organism Allium cepa

Publication

Combined strategy for phytotoxicity enhancement of benzoxazinones.
Macías FA, Chinchilla N, Arroyo E, Molinillo JM, Marín D, Varela RM.
J Agric Food Chem (2010) 58 : 2047 -2053
PubMed 20014762 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
GI 15 - -
IC50 4 6.27 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2228073 6-Cl-4-Val-D-DIBOA — 2 6.70
CHEMBL2228072 6-Cl-4-Pr-D-DIBOA — 2 6.70
CHEMBL2228069 6-F-2-Et-D-DIBOA — 2 5.89
CHEMBL2228074 6-Cl-2-Et-D-DIBOA — 2 5.80
CHEMBL2228081 8-Cl-2-Ph-D-DIBOA — 1 -
CHEMBL2228080 8-Cl-2-Pr-D-DIBOA — 1 -
CHEMBL2228079 8-Cl-2-Et-D-DIBOA — 1 -
CHEMBL2228078 8-Cl-4-Val-D-DIBOA — 1 -
CHEMBL2228077 8-Cl-4-Pr-D-DIBOA — 1 -
CHEMBL2228076 6-Cl-2-Ph-D-DIBOA — 1 -
CHEMBL2228075 6-Cl-2-Pr-D-DIBOA — 1 -
CHEMBL2228071 6-F-2-Ph-D-DIBOA — 1 -
CHEMBL2228070 6-F-2-Pr-D-DIBOA — 1 -
CHEMBL2228068 6-F-4-Val-D-DIBOA — 1 -
CHEMBL2228067 6F-4Pr-D-DIBOA — 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2228072 6-Cl-4-Pr-D-DIBOA IC50 = 200.0 nM 6.70
CHEMBL2228073 6-Cl-4-Val-D-DIBOA IC50 = 200.0 nM 6.70
CHEMBL2228069 6-F-2-Et-D-DIBOA IC50 = 1300.0 nM 5.89
CHEMBL2228074 6-Cl-2-Et-D-DIBOA IC50 = 1600.0 nM 5.80
CHEMBL2228080 8-Cl-2-Pr-D-DIBOA GI - — -
CHEMBL2228079 8-Cl-2-Et-D-DIBOA GI - — -
CHEMBL2228078 8-Cl-4-Val-D-DIBOA GI - — -
CHEMBL2228077 8-Cl-4-Pr-D-DIBOA GI - — -
CHEMBL2228076 6-Cl-2-Ph-D-DIBOA GI - — -
CHEMBL2228075 6-Cl-2-Pr-D-DIBOA GI - — -
CHEMBL2228074 6-Cl-2-Et-D-DIBOA GI - — -
CHEMBL2228073 6-Cl-4-Val-D-DIBOA GI - — -
CHEMBL2228072 6-Cl-4-Pr-D-DIBOA GI - — -
CHEMBL2228071 6-F-2-Ph-D-DIBOA GI - — -
CHEMBL2228070 6-F-2-Pr-D-DIBOA GI - — -
CHEMBL2228069 6-F-2-Et-D-DIBOA GI - — -
CHEMBL2228068 6-F-4-Val-D-DIBOA GI - — -
CHEMBL2228081 8-Cl-2-Ph-D-DIBOA GI - — -
CHEMBL2228067 6F-4Pr-D-DIBOA GI - — -