Assay Detail
Binding
CHEMBL859456
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Compound was tested for its binding affinity against Alpha-1 adrenergic receptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
N,N-6-bis-[2-(3,4-dihydroxybenzyl)pyrrolidinyl]hexane, a potent, selective, orally active dopamine analog with hypotensive and diuretic activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.35 | 7.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL310997 | — | — | 1 | 7.25 |
| CHEMBL588 | FENOLDOPAM | 4.0 | 1 | 6.82 |
| CHEMBL308295 | — | — | 1 | 6.41 |
| CHEMBL80686 | — | — | 1 | 6.41 |
| CHEMBL80974 | — | — | 1 | 6.24 |
| CHEMBL15564 | — | — | 1 | 5.70 |
| CHEMBL59 | DOPAMINE | 4.0 | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL310997 | — | Ki | = | 56.23 | nM | 7.25 |
| CHEMBL588 | FENOLDOPAM | Ki | = | 151.36 | nM | 6.82 |
| CHEMBL308295 | — | Ki | = | 389.05 | nM | 6.41 |
| CHEMBL80686 | — | Ki | = | 389.05 | nM | 6.41 |
| CHEMBL80974 | — | Ki | = | 575.44 | nM | 6.24 |
| CHEMBL15564 | — | Ki | = | 1995.26 | nM | 5.70 |
| CHEMBL59 | DOPAMINE | Ki | = | 2511.89 | nM | 5.60 |