Compound Detail
CHEMBL103396
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Basic Information
| ChEMBL ID | CHEMBL103396 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OJYUNKKSBJSEAT-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
193.2
MW (Da)
-0.58
ALogP
4
HBA
4
HBD
100.6
PSA (Ų)
0.35
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 5.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamyl aminopeptidase CHEMBL3439 | Ki | 5.46 | 5.46 | 3500.0 | 1 |
| Aminopeptidase N CHEMBL2590 | Ki | 5.35 | 5.35 | 4500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamyl aminopeptidase | Ki | = | 3500.0 | nM | 5.46 | Inhibition of aminopeptidase A (APA) | 7915326 |
| Aminopeptidase N | Ki | = | 4500.0 | nM | 5.35 | Inhibitory potency was measured on aminopeptidase N (APN) | 7915326 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7915326 | 10.1021/jm00044a016 | Glutamyl aminopeptidase | 1 |
| 7915326 | 10.1021/jm00044a016 | Aminopeptidase N | 1 |
Data from ChEMBL 36 via Core Engine