Compound Detail
CHEMBL1256472
CYTARABINE HYDROCHLORIDE 🧪 Phase III
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase III
1
Targets
4
Activities
2
Assay Types
0
PK Parameters
1
Publications
5
Known Names
3
Indications
Molecular Properties
243.2
MW (Da)
-2.56
ALogP
8
HBA
4
HBD
130.8
PSA (Ų)
0.45
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Single Enantiomer |
Indications
Leukemia, Myeloid, Acute Leukemia Leukemia, Myeloid
Activity Summary
EC50 3 meas. best 6.97
IC50 1 meas. best 5.89
Target Activity Profile
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 108.0 | nM | 6.97 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response to Identify Inhibitors o... | - |
| Unchecked | EC50 | = | 397.0 | nM | 6.4 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response to Identify Inhibitors o... | - |
| Unchecked | EC50 | = | 431.0 | nM | 6.37 | PUBCHEM_BIOASSAY: Luminescence Cell-Based HTS Dose Confirmation to Identify Inhi... | - |
| Unchecked | IC50 | = | 1299.0 | nM | 5.89 | PUBCHEM_BIOASSAY: Luminescence-based dose response cell-based high throughput sc... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17417631 | 10.1038/nchembio873 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine