Compound Detail
CHEMBL1359526
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Basic Information
| ChEMBL ID | CHEMBL1359526 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UVEURIRRRLDTGG-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
293.3
MW (Da)
1.70
ALogP
4
HBA
0
HBD
70.3
PSA (Ų)
0.60
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.37
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 5.37 | 5.37 | 4320.0 | 1 |
| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 CHEMBL1795098 | IC50 | 4.89 | 4.89 | 12914.0 | 1 |
| Eukaryotic translation initiation factor 4H CHEMBL1293274 | IC50 | 4.32 | 4.32 | 48285.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 | IC50 | = | 4320.0 | nM | 5.37 | PUBCHEM_BIOASSAY: uHTS fluorescence polarization assay for the identification of... | - |
| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 | IC50 | = | 12914.0 | nM | 4.89 | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for Scp-1 phosphatase ... | - |
| Eukaryotic translation initiation factor 4H | IC50 | = | 48285.0 | nM | 4.32 | PUBCHEM_BIOASSAY: uHTS fluorescence polarization assay for the identification of... | - |
Data from ChEMBL 36 via Core Engine