Compound Detail
CHEMBL1362862
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Basic Information
| ChEMBL ID | CHEMBL1362862 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BNGSYLQFZPCEHU-UHFFFAOYSA-N |
3
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
349.4
MW (Da)
4.31
ALogP
4
HBA
2
HBD
72.5
PSA (Ų)
0.70
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.75
IC50 1 meas. best 4.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.75 | 4.75 | 17927.0 | 1 |
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 4.7 | 4.7 | 20000.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.54 | 4.54 | 29160.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein mex-5 | EC50 | = | 17927.0 | nM | 4.75 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Polyadenylate-binding protein 1 | IC50 | = | 20000.0 | nM | 4.7 | PUBCHEM_BIOASSAY: Dose-response confirmation of microRNA-mediated mRNA deacetyla... | - |
| RNA-binding protein pos-1 | EC50 | = | 29160.0 | nM | 4.54 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine