Compound Detail
CHEMBL1380684
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Basic Information
| ChEMBL ID | CHEMBL1380684 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SKYZYDSNJIOXRL-ZOWNYOTGSA-N |
| Parent Compound | CHEMBL416288 |
| Active Moiety | CHEMBL416288 |
6
Targets
9
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
267.3
MW (Da)
2.85
ALogP
3
HBA
2
HBD
43.7
PSA (Ų)
0.72
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 5.51
Ki 1 meas. best 5.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Disabled homolog 2-interacting protein CHEMBL4523330 | Ki | 5.72 | 5.72 | 1920.0 | 1 |
| Aspartyl aminopeptidase CHEMBL1293263 | IC50 | 5.51 | 5.51 | 3103.0 | 1 |
| Runt-related transcription factor 1/Core-binding factor subunit beta CHEMBL2093862 | IC50 | 5.15 | 5.03 | 7120.0 | 4 |
| Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase CHEMBL1741212 | IC50 | 5.08 | 5.08 | 8360.0 | 1 |
| Mannose-6-phosphate isomerase CHEMBL2758 | IC50 | 4.6 | 4.6 | 24926.0 | 1 |
| Glucose-6-phosphate 1-dehydrogenase CHEMBL5347 | IC50 | 4.42 | 4.42 | 38400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine