Compound Detail
CHEMBL1419164
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Basic Information
| ChEMBL ID | CHEMBL1419164 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WJOXYTHYWUBLQU-UHFFFAOYSA-N |
3
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
303.3
MW (Da)
3.34
ALogP
3
HBA
1
HBD
57.6
PSA (Ų)
0.74
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 5 meas. best 7.09
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 7.09 | 5.47 | 82.0 | 3 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 6.74 | 6.74 | 183.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.58 | 5.58 | 2619.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 82.0 | nM | 7.09 | PUBCHEM_BIOASSAY: Fluorescence Cell-Based Retest of Candida albicans Growth in t... | - |
| Zinc finger protein mex-5 | EC50 | = | 183.0 | nM | 6.74 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 2619.0 | nM | 5.58 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Unchecked | EC50 | = | 5650.0 | nM | 5.25 | PUBCHEM_BIOASSAY: HCS for Compounds that Up-Regulate Insulin Promoter Activity i... | - |
| Unchecked | EC50 | = | 85678.0 | nM | 4.07 | PUBCHEM_BIOASSAY: Fluorescence Cell-Based Secondary Assay for toxicity in mammal... | - |
Data from ChEMBL 36 via Core Engine