Compound Detail
CHEMBL1422105
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Basic Information
| ChEMBL ID | CHEMBL1422105 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FEKKWERVLUQMGF-UHFFFAOYSA-N |
3
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
464.6
MW (Da)
3.87
ALogP
6
HBA
3
HBD
94.5
PSA (Ų)
0.62
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 5 meas. best 6.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 6.02 | 6.02 | 959.0 | 1 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.79 | 5.6267 | 1606.0 | 3 |
| Streptococcus CHEMBL612313 | EC50 | 5.37 | 5.37 | 4320.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Streptococcus sp. 'group A' | EC50 | = | 959.0 | nM | 6.02 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Streptokinase A | EC50 | = | 1606.0 | nM | 5.79 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response Follow up to Iden... | - |
| Streptokinase A | EC50 | = | 2436.0 | nM | 5.61 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Streptokinase A | EC50 | = | 3323.0 | nM | 5.48 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify I... | - |
| Streptococcus | EC50 | = | 4320.0 | nM | 5.37 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Response Follow up to Id... | - |
Data from ChEMBL 36 via Core Engine