Compound Detail
CHEMBL1449558
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Basic Information
| ChEMBL ID | CHEMBL1449558 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VKLJERDOVVPTLR-UHFFFAOYSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
426.9
MW (Da)
3.43
ALogP
7
HBA
0
HBD
61.8
PSA (Ų)
0.46
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 4 meas. best 5.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Streptokinase A CHEMBL1293228 | EC50 | 5.64 | 5.28 | 2302.0 | 3 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.1 | 5.1 | 7960.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Streptokinase A | EC50 | = | 2302.0 | nM | 5.64 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Streptokinase A | EC50 | = | 5898.0 | nM | 5.23 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response Follow up to Iden... | - |
| Streptococcus sp. 'group A' | EC50 | = | 7960.0 | nM | 5.1 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Streptokinase A | EC50 | = | 10702.0 | nM | 4.97 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify I... | - |
Data from ChEMBL 36 via Core Engine