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Compound Detail

CHEMBL1479301

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CCCCCC(=O)N[C@@H](c1ccccc1)[C@@H](O)C(=O)O[C@H]1C[C@@]2(O)[C@@H](OC(=O)c3ccccc3)C3[C@](C)(C(=O)[C@H](OC(C)=O)C(=C1C)C2(C)C)[C@@H](O)C[C@H]1OC[C@@]31OC(C)=O

Basic Information

ChEMBL ID CHEMBL1479301
Phase Preclinical
Structure Type MOL
InChI Key BEHTXUBGUDGCNQ-QJUJXNPASA-N
1
Targets
5
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

848.0
MW (Da)
4.00
ALogP
14
HBA
4
HBD
221.3
PSA (Ų)
0.10
QED
2
Ro5 Violations
13
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C46H57NO14
MW 847.95
Aromatic Rings 2
Heavy Atoms 61
NP-Likeness 1.95

Activity Summary

EC50 3 meas. best 6.64
IC50 2 meas. best 7.21

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 7.21 5.85 61.8 2
Unchecked
CHEMBL612545
EC50 6.64 6.5467 229.0 3

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine