Compound Detail
CHEMBL1482979
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1482979 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SWUMELJEILBEEI-OQLLNIDSSA-N |
4
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
399.4
MW (Da)
2.92
ALogP
6
HBA
2
HBD
102.7
PSA (Ų)
0.32
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.42
IC50 1 meas. best 5.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein-tyrosine kinase 2-beta CHEMBL5469 | IC50 | 5.42 | 5.42 | 3765.0 | 1 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.42 | 5.42 | 3845.0 | 1 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.08 | 5.08 | 8315.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 4.37 | 4.37 | 42900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Streptococcus sp. 'group A' | EC50 | = | 3845.0 | nM | 5.42 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Protein-tyrosine kinase 2-beta | IC50 | = | 3765.0 | nM | 5.42 | PUBCHEM_BIOASSAY: TR-FRET counterscreen for FAK inhibitors: dose-response bioche... | - |
| Streptokinase A | EC50 | = | 8315.0 | nM | 5.08 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify I... | - |
| Unchecked | EC50 | = | 42900.0 | nM | 4.37 | PUBCHEM_BIOASSAY: Dose response counterscreen for uHTS small molecule activators... | - |
Data from ChEMBL 36 via Core Engine