Compound Detail
CHEMBL1484942
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1484942 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DCXGIVFPYWVAGY-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
265.4
MW (Da)
3.41
ALogP
3
HBA
2
HBD
41.8
PSA (Ų)
0.50
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 7 CHEMBL2219 | IC50 | 5.55 | 5.55 | 2820.0 | 1 |
| Dual specificity protein phosphatase 3 CHEMBL2635 | IC50 | 5.47 | 5.06 | 3400.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 7 | IC50 | = | 2820.0 | nM | 5.55 | PUBCHEM_BIOASSAY: MOA HePTP Fluorescent secondary assay for identification of re... | - |
| Dual specificity protein phosphatase 3 | IC50 | = | 3400.0 | nM | 5.47 | PUBCHEM_BIOASSAY: MOA VHR1 Fluorescent secondary assay for identification of red... | - |
| Dual specificity protein phosphatase 3 | IC50 | = | 22500.0 | nM | 4.65 | PUBCHEM_BIOASSAY: SAR VHR1 Fluorescent Assay for In Vitro dose response studies.... | - |
Data from ChEMBL 36 via Core Engine