Compound Detail
CHEMBL1500850
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Basic Information
| ChEMBL ID | CHEMBL1500850 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NFPAYMHTJZCVDP-RIYZIHGNSA-N |
4
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
371.4
MW (Da)
3.29
ALogP
6
HBA
3
HBD
129.3
PSA (Ų)
0.44
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.84
IC50 2 meas. best 4.73
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 5.84 | 5.84 | 1451.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.39 | 5.39 | 4095.0 | 1 |
| Aminopeptidase N CHEMBL4117 | IC50 | 4.73 | 4.73 | 18470.0 | 1 |
| RNA-editing ligase 1, mitochondrial CHEMBL4105928 | IC50 | 4.11 | 4.11 | 77911.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein mex-5 | EC50 | = | 1451.0 | nM | 5.84 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 4095.0 | nM | 5.39 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Aminopeptidase N | IC50 | = | 18470.0 | nM | 4.73 | PUBCHEM_BIOASSAY: Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopep... | - |
| RNA-editing ligase 1, mitochondrial | IC50 | = | 77911.0 | nM | 4.11 | PubChem BioAssay. Fluorescence-based biochemical high throughput dose response a... | - |
Data from ChEMBL 36 via Core Engine