Compound Detail
CHEMBL1520090
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Basic Information
| ChEMBL ID | CHEMBL1520090 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AIJDOUMFCZTCAH-RSAXXLAASA-N |
| Parent Compound | CHEMBL1623146 |
| Active Moiety | CHEMBL1623146 |
3
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
322.5
MW (Da)
0.72
ALogP
6
HBA
2
HBD
89.1
PSA (Ų)
0.65
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.58
IC50 1 meas. best 4.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 4.68 | 4.68 | 21000.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.58 | 4.58 | 26129.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.5 | 4.5 | 31850.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 | IC50 | = | 21000.0 | nM | 4.68 | PUBCHEM_BIOASSAY: Dose-response confirmation of microRNA-mediated mRNA deacetyla... | - |
| Zinc finger protein mex-5 | EC50 | = | 26129.0 | nM | 4.58 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 31850.0 | nM | 4.5 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine