Compound Detail
CHEMBL1556750
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Basic Information
| ChEMBL ID | CHEMBL1556750 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FOGMNOHCZQDZGD-UHFFFAOYSA-N |
3
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
272.7
MW (Da)
2.79
ALogP
2
HBA
1
HBD
41.5
PSA (Ų)
0.52
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.57
IC50 2 meas. best 6.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.28 | 6.08 | 520.0 | 2 |
| Protein RecA CHEMBL1741171 | EC50 | 5.57 | 5.57 | 2710.0 | 1 |
| Endoribonuclease toxin MazF CHEMBL1795096 | EC50 | 4.21 | 4.21 | 61200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 520.0 | nM | 6.28 | PUBCHEM_BIOASSAY: High Throughput Screening Assay used to Identify Novel Compoun... | - |
| Unchecked | IC50 | = | 1320.0 | nM | 5.88 | PUBCHEM_BIOASSAY: A High Throughput Confirmatory Assay used to Identify Novel Co... | - |
| Protein RecA | EC50 | = | 2710.0 | nM | 5.57 | PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inh... | - |
| Endoribonuclease toxin MazF | EC50 | = | 61200.0 | nM | 4.21 | PUBCHEM_BIOASSAY: Dose response confirmation uHTS hits for MazEF TA System activ... | - |
Data from ChEMBL 36 via Core Engine