Compound Detail
CHEMBL1559259
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Basic Information
| ChEMBL ID | CHEMBL1559259 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GALUEGSXWCYSQD-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
392.4
MW (Da)
4.06
ALogP
7
HBA
0
HBD
74.3
PSA (Ų)
0.29
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein CHEMBL3885546 | IC50 | 6.07 | 6.07 | 858.0 | 1 |
| Neuropeptide Y receptor type 2 CHEMBL4018 | IC50 | 5.5 | 5.5 | 3137.0 | 1 |
| Neuropeptide Y receptor type 1 CHEMBL4777 | IC50 | 5.28 | 5.28 | 5210.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein | IC50 | = | 858.0 | nM | 6.07 | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule ant... | - |
| Neuropeptide Y receptor type 2 | IC50 | = | 3137.0 | nM | 5.5 | PUBCHEM_BIOASSAY: Dose response cell-based screening assay for antagonists of ne... | - |
| Neuropeptide Y receptor type 1 | IC50 | = | 5210.0 | nM | 5.28 | PUBCHEM_BIOASSAY: Dose response counterscreen for neuropeptide Y receptor Y2 (NP... | - |
Data from ChEMBL 36 via Core Engine