Compound Detail
CHEMBL1568292
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1568292 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BNQVUQSZXQSEBE-UHFFFAOYSA-N |
4
Targets
5
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
271.3
MW (Da)
3.35
ALogP
3
HBA
2
HBD
63.2
PSA (Ų)
0.90
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.15
EC50 2 meas. best 4.56
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 CHEMBL1293302 | IC50 | 5.15 | 5.15 | 7148.0 | 1 |
| Protein Rev CHEMBL1293282 | IC50 | 4.94 | 4.94 | 11406.0 | 1 |
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 4.66 | 4.66 | 21800.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.56 | 4.56 | 27376.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 | IC50 | = | 7148.0 | nM | 5.15 | PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput do... | - |
| Protein Rev | IC50 | = | 11406.0 | nM | 4.94 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of gld-1: Fluorescence polarizati... | - |
| Polyadenylate-binding protein 1 | IC50 | = | 21800.0 | nM | 4.66 | PUBCHEM_BIOASSAY: Dose-response confirmation of microRNA-mediated mRNA deacetyla... | - |
| Zinc finger protein mex-5 | EC50 | = | 27376.0 | nM | 4.56 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine