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Compound Detail

CHEMBL1574553

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Brc1ccc(N=Nc2ccc3ccccc3n2)cc1

Basic Information

ChEMBL ID CHEMBL1574553
Phase Preclinical
Structure Type MOL
InChI Key JHSZMQCXWKUICJ-UHFFFAOYSA-N
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

312.2
MW (Da)
5.41
ALogP
3
HBA
0
HBD
37.6
PSA (Ų)
0.58
QED
1
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H10BrN3
MW 312.17
Aromatic Rings 3
Heavy Atoms 19
NP-Likeness -0.90

Activity Summary

EC50 4 meas. best 6.97

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 6.97 6.6267 107.0 3
Luciferin 4-monooxygenase
CHEMBL5567
EC50 6.52 6.52 299.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine