Compound Detail
CHEMBL1582403
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Basic Information
| ChEMBL ID | CHEMBL1582403 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BQLBXGYOYZGYER-LRVNMVSOSA-N |
3
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
386.5
MW (Da)
4.19
ALogP
7
HBA
1
HBD
95.2
PSA (Ų)
0.61
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.36
IC50 1 meas. best 4.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.36 | 5.36 | 4357.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 5.16 | 5.16 | 6851.0 | 1 |
| Estrogen receptor CHEMBL206 | IC50 | 4.68 | 4.68 | 21012.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RNA-binding protein pos-1 | EC50 | = | 4357.0 | nM | 5.36 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Zinc finger protein mex-5 | EC50 | = | 6851.0 | nM | 5.16 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Estrogen receptor | IC50 | = | 21012.5 | nM | 4.68 | PUBCHEM_BIOASSAY: Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Re... | - |
Data from ChEMBL 36 via Core Engine