Compound Detail
CHEMBL1584730
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Basic Information
| ChEMBL ID | CHEMBL1584730 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LOWLDAFNDBTEJX-UHFFFAOYSA-N |
3
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
348.4
MW (Da)
1.91
ALogP
5
HBA
3
HBD
112.3
PSA (Ų)
0.66
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.8
IC50 1 meas. best 4.59
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 5.8 | 5.8 | 1585.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.28 | 5.28 | 5249.0 | 1 |
| Estrogen receptor beta CHEMBL242 | IC50 | 4.59 | 4.59 | 25929.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein mex-5 | EC50 | = | 1585.0 | nM | 5.8 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 5249.0 | nM | 5.28 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Estrogen receptor beta | IC50 | = | 25929.39 | nM | 4.59 | PUBCHEM_BIOASSAY: Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Res... | - |
Data from ChEMBL 36 via Core Engine