Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1629985

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
O=C1/C(=C/c2ccncc2)CNC/C1=C\c1ccncc1

Basic Information

ChEMBL ID CHEMBL1629985
Phase Preclinical
Structure Type MOL
InChI Key LJTXXPUSSOVJDM-KAVGSWPWSA-N
5
Targets
7
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

277.3
MW (Da)
2.12
ALogP
4
HBA
1
HBD
54.9
PSA (Ų)
0.85
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H15N3O
MW 277.33
Aromatic Rings 2
Heavy Atoms 21
NP-Likeness -0.27

Activity Summary

IC50 7 meas. best 6.1

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
HeLa
CHEMBL399
IC50 6.1 6.1 800.0 1
CCRF-CEM
CHEMBL382
IC50 5.77 5.77 1700.0 1
NON-PROTEIN TARGET
CHEMBL3879801
IC50 5.3 5.1967 5000.0 3
L1210
CHEMBL386
IC50 5.05 5.05 8900.0 1
A549
CHEMBL392
IC50 4.99 4.99 10300.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine