Compound Detail
CHEMBL1975006
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1975006 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZFULGBFZQJLCRE-LICLKQGHSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
285.3
MW (Da)
1.95
ALogP
5
HBA
2
HBD
83.8
PSA (Ų)
0.65
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tegument protein VP16 CHEMBL4218 | IC50 | 5.07 | 5.07 | 8437.0 | 1 |
| Nuclear receptor coactivator 3 CHEMBL1615382 | IC50 | 5.01 | 5.01 | 9666.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tegument protein VP16 | IC50 | = | 8437.0 | nM | 5.07 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of the Steroid Receptor Coactivat... | - |
| Nuclear receptor coactivator 3 | IC50 | = | 9666.0 | nM | 5.01 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of the Steroid Receptor Coactivat... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28302506 | 10.1016/j.bmc.2017.02.044 | Xanthine dehydrogenase/oxidase | 1 |
Data from ChEMBL 36 via Core Engine