Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL3262942

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CC(C)CC(CC(=O)OCC1(CO)C/C(=C\c2ccc(C(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc2)C(=O)O1)CC(C)C

Basic Information

ChEMBL ID CHEMBL3262942
Phase Preclinical
Structure Type MOL
InChI Key FMSODUNQUKNILA-WPWMEQJKSA-N
2
Targets
5
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

616.8
MW (Da)
6.16
ALogP
9
HBA
1
HBD
125.4
PSA (Ų)
0.12
QED
2
Ro5 Violations
13
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C35H52O9
MW 616.79
Aromatic Rings 1
Heavy Atoms 44
NP-Likeness 0.60

Activity Summary

Ki 4 meas. best 9.22
Kd 1 meas. best 9.22

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Protein kinase C delta type
CHEMBL2560
Kd 9.22 9.22 0.6 1
Unchecked
CHEMBL612545
Ki 9.22 8.8175 0.6 4

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
24684293 10.1021/jm500165n Unchecked 16
24684293 10.1021/jm500165n Protein kinase C delta type 1

Data from ChEMBL 36 via Core Engine