Compound Detail
CHEMBL3290762
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3290762 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MOANORSVXVOLHK-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
301.3
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HL-60 CHEMBL383 | IC50 | 5.7 | 5.65 | 2000.0 | 2 |
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 5.05 | 5.05 | 9000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HL-60 | IC50 | = | 2000.0 | nM | 5.7 | Cytotoxicity against human HL60 cells assessed as inhibition of proliferation af... | 24867309 |
| HL-60 | IC50 | = | 2500.0 | nM | 5.6 | Cytotoxicity against human HL60 cells assessed as inhibition of proliferation af... | 24867309 |
| NON-PROTEIN TARGET | IC50 | = | 9000.0 | nM | 5.05 | Cytotoxicity against human SSMC-7721 cells assessed as inhibition of proliferati... | 24867309 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24867309 | 10.1021/jm500221p | HL-60 | 2 |
| 24867309 | 10.1021/jm500221p | NON-PROTEIN TARGET | 1 |
| 24867309 | 10.1021/jm500221p | HeLa | 1 |
| 24867309 | 10.1021/jm500221p | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine