Compound Detail
CHEMBL3290763
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Basic Information
| ChEMBL ID | CHEMBL3290763 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JQCXKQIFHMTDBV-UHFFFAOYSA-N |
3
Targets
4
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
315.3
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HL-60 CHEMBL383 | IC50 | 6.16 | 6.13 | 700.0 | 2 |
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 5.47 | 5.47 | 3400.0 | 1 |
| HeLa CHEMBL399 | IC50 | 5.34 | 5.34 | 4600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HL-60 | IC50 | = | 700.0 | nM | 6.16 | Cytotoxicity against human HL60 cells assessed as inhibition of proliferation af... | 24867309 |
| HL-60 | IC50 | = | 800.0 | nM | 6.1 | Cytotoxicity against human HL60 cells assessed as inhibition of proliferation af... | 24867309 |
| NON-PROTEIN TARGET | IC50 | = | 3400.0 | nM | 5.47 | Cytotoxicity against human SSMC-7721 cells assessed as inhibition of proliferati... | 24867309 |
| HeLa | IC50 | = | 4600.0 | nM | 5.34 | Cytotoxicity against human HeLa cells assessed as inhibition of proliferation af... | 24867309 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24867309 | 10.1021/jm500221p | HL-60 | 2 |
| 24867309 | 10.1021/jm500221p | NON-PROTEIN TARGET | 1 |
| 24867309 | 10.1021/jm500221p | HeLa | 1 |
| 24867309 | 10.1021/jm500221p | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine