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Compound Detail

CHEMBL340597

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CC(=O)c1ccc(C2=CN3CCC2CC3)o1

Basic Information

ChEMBL ID CHEMBL340597
Phase Preclinical
Structure Type MOL
InChI Key LSYQABJIACQBKK-UHFFFAOYSA-N
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

217.3
MW (Da)
2.55
ALogP
3
HBA
0
HBD
33.5
PSA (Ų)
0.71
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C13H15NO2
MW 217.27
Aromatic Rings 1
Heavy Atoms 16
NP-Likeness -0.08

Activity Summary

Ki 4 meas. best 5.96

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Muscarinic acetylcholine receptor
CHEMBL2094109
Ki 5.96 5.58 1100.0 4

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
9371246 10.1021/jm970346t Muscarinic acetylcholine receptor 4

Data from ChEMBL 36 via Core Engine