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Compound Detail

CHEMBL367128

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C[C@@H]1OCC2(CN3CCC2CC3)O1.C[C@H]1OCC2(CN3CCC2CC3)O1

Basic Information

ChEMBL ID CHEMBL367128
Phase Preclinical
Structure Type MOL
InChI Key RLZMELVJWCYHEW-HBBRWFBTSA-N
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

366.5
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H34N2O4
MW 366.50

Activity Summary

EC50 3 meas. best 5.48

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Cavia porcellus
CHEMBL369
EC50 5.48 5.07 3311.3 2
Rattus norvegicus
CHEMBL376
EC50 5.24 5.24 5754.4 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
3585909 10.1021/jm00389a003 Cavia porcellus 4
3585909 10.1021/jm00389a003 Rattus norvegicus 2
3585909 10.1021/jm00389a003 Muscarinic acetylcholine receptor M2 1
3585909 10.1021/jm00389a003 Muscarinic acetylcholine receptor M1 1
3585909 10.1021/jm00389a003 Muscarinic acetylcholine receptors; M1 & M2 1

Data from ChEMBL 36 via Core Engine