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Compound Detail

CHEMBL5561051

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CC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NN)C(c1ccccc1)c1ccccc1

Basic Information

ChEMBL ID CHEMBL5561051
Phase Preclinical
Structure Type MOL
InChI Key NEBWARUTOFCQKF-SCHANZIDSA-N
6
Targets
9
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

1496.9
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C80H109N19O10
MW 1496.88

Activity Summary

IC50 9 meas. best 4.83

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
A20
CHEMBL613850
IC50 4.83 4.83 14900.0 1
Unchecked
CHEMBL612545
IC50 4.72 4.72 18900.0 1
U-937
CHEMBL612794
IC50 4.59 4.59 25500.0 1
HeLa
CHEMBL399
IC50 4.28 4.28 52700.0 1
ES-2
CHEMBL5058622
IC50 4.28 4.28 52000.0 1
NCI/ADR-RES
CHEMBL613829
IC50 4.18 4.18 66000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine