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Compound Detail

CHEMBL5561453

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NCCCC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)NN)C(c1ccccc1)c1ccccc1

Basic Information

ChEMBL ID CHEMBL5561453
Phase Preclinical
Structure Type MOL
InChI Key VTNVKOFDZZAMIE-WCRWLLLKSA-N
5
Targets
9
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

1454.8
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C78H107N19O9
MW 1454.84

Activity Summary

IC50 9 meas. best 5.01

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
A20
CHEMBL613850
IC50 5.01 5.01 9800.0 1
U-937
CHEMBL612794
IC50 4.98 4.98 10500.0 1
Unchecked
CHEMBL612545
IC50 4.9 4.9 12600.0 1
HeLa
CHEMBL399
IC50 4.35 4.35 44300.0 1
NCI/ADR-RES
CHEMBL613829
IC50 4.32 4.32 47600.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine