Assay Detail
Binding
CHEMBL1645740
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Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curves
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Characterization and anions inhibition studies of an α-carbonic anhydrase from the teleost fish Dicentrarchus labrax.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 4.48 | 6.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL68253 | SULFAMATE | — | 1 | 6.03 |
| CHEMBL1644027 | POTASSIUM FLUORIDE | — | 1 | 4.16 |
| CHEMBL1141 | POTASSIUM IODIDE | 4.0 | 1 | 4.10 |
| CHEMBL1644030 | POTASSIUM BROMIDE | -1.0 | 1 | 4.05 |
| CHEMBL1200731 | POTASSIUM CHLORIDE | 4.0 | 1 | 4.05 |
| CHEMBL1644028 | THIOCYANATE SODIUM | -1.0 | 1 | - |
| CHEMBL1644029 | POTASSIUM NITRATE | 4.0 | 1 | - |
| CHEMBL93268 | SODIUM NITRITE | 4.0 | 1 | - |
| CHEMBL89295 | SODIUM AZIDE | — | 1 | - |
| CHEMBL233406 | SODIUM SULFATE ANHYDROUS | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL68253 | SULFAMATE | Ki | = | 930.0 | nM | 6.03 |
| CHEMBL1644027 | POTASSIUM FLUORIDE | Ki | = | 70000.0 | nM | 4.16 |
| CHEMBL1141 | POTASSIUM IODIDE | Ki | = | 80000.0 | nM | 4.10 |
| CHEMBL1644030 | POTASSIUM BROMIDE | Ki | = | 90000.0 | nM | 4.05 |
| CHEMBL1200731 | POTASSIUM CHLORIDE | Ki | = | 90000.0 | nM | 4.05 |
| CHEMBL1644028 | THIOCYANATE SODIUM | Ki | = | 39000000.0 | nM | - |
| CHEMBL1644029 | POTASSIUM NITRATE | Ki | = | 58700000.0 | nM | - |
| CHEMBL93268 | SODIUM NITRITE | Ki | = | 30800000.0 | nM | - |
| CHEMBL89295 | SODIUM AZIDE | Ki | = | 65100000.0 | nM | - |
| CHEMBL233406 | SODIUM SULFATE ANHYDROUS | Ki | = | 9000000.0 | nM | - |