Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1963761

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MAPK13
ChEMBL ↗
739
Total Activities
728
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mitogen-activated protein kinase 13 (CHEMBL2939) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 739 5.86 7.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1999931 — — 1 7.50
CHEMBL103667 DORAMAPIMOD 2.0 1 7.30
CHEMBL396523 — — 1 7.20
CHEMBL1981079 — — 1 7.20
CHEMBL1965660 — — 2 7.20
CHEMBL1977223 — — 1 7.10
CHEMBL244378 — — 1 7.10
CHEMBL225519 — — 1 7.10
CHEMBL411903 — — 1 7.00
CHEMBL1986943 — — 2 6.90
CHEMBL2003638 — — 1 6.90
CHEMBL1997129 — — 1 6.90
CHEMBL1998585 — — 1 6.90
CHEMBL260092 — — 1 6.80
CHEMBL1987034 — — 1 6.80
CHEMBL1970083 — — 1 6.70
CHEMBL1980995 — — 1 6.70
CHEMBL1988387 — — 1 6.70
CHEMBL1997759 — — 1 6.60
CHEMBL1978448 — — 1 6.60
CHEMBL1984162 — — 1 6.50
CHEMBL243088 — — 1 6.40
CHEMBL1995813 — — 1 6.40
CHEMBL1987054 — — 1 6.30
CHEMBL1964290 — — 1 6.30
CHEMBL422897 — — 1 6.30
CHEMBL1991078 — — 1 6.30
CHEMBL1974870 — — 1 6.20
CHEMBL1969588 — — 1 6.20
CHEMBL1991063 — — 1 6.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1999931 — Ki = 31.62 nM 7.50
CHEMBL103667 DORAMAPIMOD Ki = 50.12 nM 7.30
CHEMBL396523 — Ki = 63.1 nM 7.20
CHEMBL1965660 — Ki = 63.1 nM 7.20
CHEMBL1965660 — Ki = 63.1 nM 7.20
CHEMBL1981079 — Ki = 63.1 nM 7.20
CHEMBL244378 — Ki = 79.43 nM 7.10
CHEMBL1977223 — Ki = 79.43 nM 7.10
CHEMBL225519 — Ki = 79.43 nM 7.10
CHEMBL411903 — Ki = 100.0 nM 7.00
CHEMBL1998585 — Ki = 125.89 nM 6.90
CHEMBL1986943 — Ki = 125.89 nM 6.90
CHEMBL1997129 — Ki = 125.89 nM 6.90
CHEMBL1986943 — Ki = 125.89 nM 6.90
CHEMBL2003638 — Ki = 125.89 nM 6.90
CHEMBL1987034 — Ki = 158.49 nM 6.80
CHEMBL260092 — Ki = 158.49 nM 6.80
CHEMBL1988387 — Ki = 199.53 nM 6.70
CHEMBL1970083 — Ki = 199.53 nM 6.70
CHEMBL1980995 — Ki = 199.53 nM 6.70
CHEMBL1978448 — Ki = 251.19 nM 6.60
CHEMBL1997759 — Ki = 251.19 nM 6.60
CHEMBL1984162 — Ki = 316.23 nM 6.50
CHEMBL243088 — Ki = 398.11 nM 6.40
CHEMBL1995813 — Ki = 398.11 nM 6.40
CHEMBL1964290 — Ki = 501.19 nM 6.30
CHEMBL1987054 — Ki = 501.19 nM 6.30
CHEMBL1991078 — Ki = 501.19 nM 6.30
CHEMBL422897 — Ki = 501.19 nM 6.30
CHEMBL1969588 — Ki = 630.96 nM 6.20
CHEMBL1974870 — Ki = 630.96 nM 6.20
CHEMBL1986263 — Ki = 630.96 nM 6.20
CHEMBL1994321 — Ki = 630.96 nM 6.20
CHEMBL1991063 — Ki = 630.96 nM 6.20
CHEMBL592030 — Ki = 630.96 nM 6.20
CHEMBL539474 — Ki = 794.33 nM 6.10
CHEMBL2001751 — Ki = 794.33 nM 6.10
CHEMBL1985095 — Ki = 794.33 nM 6.10
CHEMBL482767 SNS-314 Ki = 794.33 nM 6.10
CHEMBL1990254 — Ki = 794.33 nM 6.10
CHEMBL1966628 — Ki = 1000.0 nM 6.00
CHEMBL1972158 — Ki = 1000.0 nM 6.00
CHEMBL1973211 — Ki = 1000.0 nM 6.00
CHEMBL1986499 — Ki = 1000.0 nM 6.00
CHEMBL2005936 — Ki = 1258.93 nM 5.90
CHEMBL1983945 — Ki = 1258.93 nM 5.90
CHEMBL1682346 — Ki = 1258.93 nM 5.90
CHEMBL2006439 — Ki = 1258.93 nM 5.90
CHEMBL1965836 — Ki = 1258.93 nM 5.90
CHEMBL1991674 — Ki = 1258.93 nM 5.90