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Assay Detail

CHEMBL1963816

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CAMK1
ChEMBL ↗
708
Total Activities
695
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Calcium/calmodulin-dependent protein kinase type 1 (CHEMBL2493) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 708 5.79 7.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1980995 — — 1 7.90
CHEMBL2000271 — — 1 7.50
CHEMBL1984162 — — 1 7.10
CHEMBL1974870 — — 2 7.00
CHEMBL2002726 — — 1 6.90
CHEMBL2004716 — — 1 6.70
CHEMBL1971029 — — 1 6.60
CHEMBL1991063 — — 1 6.60
CHEMBL1987034 — — 1 6.50
CHEMBL1965836 — — 1 6.50
CHEMBL1993661 — — 1 6.50
CHEMBL1987054 — — 1 6.40
CHEMBL1998159 — — 1 6.30
CHEMBL1974328 — — 1 6.20
CHEMBL1241473 — — 1 6.10
CHEMBL1977041 — — 1 6.10
CHEMBL504950 — — 1 6.00
CHEMBL1980297 ILORASERTIB 2.0 1 6.00
CHEMBL1972584 — — 2 5.90
CHEMBL2002479 — — 1 5.90
CHEMBL2001751 — — 1 5.90
CHEMBL1979577 — — 1 5.90
CHEMBL1990885 — — 1 5.90
CHEMBL2002165 — — 1 5.80
CHEMBL2000832 — — 1 5.80
CHEMBL1965988 — — 1 5.80
CHEMBL2000685 — — 1 5.80
CHEMBL1979883 — — 1 5.80
CHEMBL1967720 — — 1 5.80
CHEMBL481491 — — 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1980995 — Ki = 12.59 nM 7.90
CHEMBL2000271 — Ki = 31.62 nM 7.50
CHEMBL1984162 — Ki = 79.43 nM 7.10
CHEMBL1974870 — Ki = 100.0 nM 7.00
CHEMBL1974870 — Ki = 100.0 nM 7.00
CHEMBL2002726 — Ki = 125.89 nM 6.90
CHEMBL2004716 — Ki = 199.53 nM 6.70
CHEMBL1971029 — Ki = 251.19 nM 6.60
CHEMBL1991063 — Ki = 251.19 nM 6.60
CHEMBL1987034 — Ki = 316.23 nM 6.50
CHEMBL1993661 — Ki = 316.23 nM 6.50
CHEMBL1965836 — Ki = 316.23 nM 6.50
CHEMBL1987054 — Ki = 398.11 nM 6.40
CHEMBL1998159 — Ki = 501.19 nM 6.30
CHEMBL1974328 — Ki = 630.96 nM 6.20
CHEMBL1241473 — Ki = 794.33 nM 6.10
CHEMBL1977041 — Ki = 794.33 nM 6.10
CHEMBL504950 — Ki = 1000.0 nM 6.00
CHEMBL1980297 ILORASERTIB Ki = 1000.0 nM 6.00
CHEMBL2002479 — Ki = 1258.93 nM 5.90
CHEMBL1990885 — Ki = 1258.93 nM 5.90
CHEMBL2001751 — Ki = 1258.93 nM 5.90
CHEMBL1972584 — Ki = 1258.93 nM 5.90
CHEMBL1979577 — Ki = 1258.93 nM 5.90
CHEMBL1972584 — Ki = 1258.93 nM 5.90
CHEMBL2002165 — Ki = 1584.89 nM 5.80
CHEMBL1967720 — Ki = 1584.89 nM 5.80
CHEMBL2000685 — Ki = 1584.89 nM 5.80
CHEMBL2000832 — Ki = 1584.89 nM 5.80
CHEMBL1965988 — Ki = 1584.89 nM 5.80
CHEMBL1979883 — Ki = 1584.89 nM 5.80
CHEMBL371206 — Ki = 1995.26 nM 5.70
CHEMBL1981725 — Ki = 1995.26 nM 5.70
CHEMBL481491 — Ki = 1995.26 nM 5.70
CHEMBL1973211 — Ki = 1995.26 nM 5.70
CHEMBL1971017 — Ki = 2511.89 nM 5.60
CHEMBL1967531 — Ki = 2511.89 nM 5.60
CHEMBL1998585 — Ki = 2511.89 nM 5.60
CHEMBL1983025 — Ki = 2511.89 nM 5.60
CHEMBL1982980 — Ki = 2511.89 nM 5.60
CHEMBL1999918 — Ki = 2511.89 nM 5.60
CHEMBL196363 — Ki = 3162.28 nM 5.50
CHEMBL1991728 — Ki = 3162.28 nM 5.50
CHEMBL592030 — Ki = 3162.28 nM 5.50
CHEMBL1966524 — Ki = 3162.28 nM 5.50
CHEMBL1988173 — Ki = 3162.28 nM 5.50
CHEMBL1997617 — Ki = 3162.28 nM 5.50
CHEMBL1969190 — Ki = 3162.28 nM 5.50
CHEMBL2000335 — Ki = 3162.28 nM 5.50
CHEMBL1968070 — Ki = 3162.28 nM 5.50