Assay Detail
Functional
CHEMBL1963825
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDK7
420
Total Activities
404
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | other |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 420 | 6.20 | 8.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1994669 | — | — | 1 | 8.50 |
| CHEMBL1966628 | — | — | 1 | 8.40 |
| CHEMBL1997554 | — | — | 1 | 8.30 |
| CHEMBL1995813 | — | — | 1 | 8.20 |
| CHEMBL1987448 | — | — | 1 | 8.20 |
| CHEMBL1984548 | — | — | 1 | 8.20 |
| CHEMBL1980407 | — | — | 1 | 8.00 |
| CHEMBL1981047 | — | — | 1 | 8.00 |
| CHEMBL1977223 | — | — | 1 | 7.90 |
| CHEMBL1084546 | PF-00562271 | 1.0 | 1 | 7.70 |
| CHEMBL1974870 | — | — | 2 | 7.70 |
| CHEMBL1990885 | — | — | 1 | 7.70 |
| CHEMBL1991063 | — | — | 1 | 7.70 |
| CHEMBL1990162 | — | — | 1 | 7.60 |
| CHEMBL1998432 | — | — | 1 | 7.60 |
| CHEMBL2007574 | — | — | 1 | 7.60 |
| CHEMBL1969588 | — | — | 1 | 7.60 |
| CHEMBL1966204 | — | — | 1 | 7.60 |
| CHEMBL1977138 | — | — | 1 | 7.50 |
| CHEMBL2005478 | — | — | 1 | 7.50 |
| CHEMBL2006456 | — | — | 1 | 7.50 |
| CHEMBL1993661 | — | — | 1 | 7.50 |
| CHEMBL1985681 | — | — | 1 | 7.40 |
| CHEMBL1982271 | — | — | 1 | 7.40 |
| CHEMBL1996980 | — | — | 1 | 7.40 |
| CHEMBL2006674 | — | — | 1 | 7.40 |
| CHEMBL1973720 | — | — | 2 | 7.30 |
| CHEMBL1983923 | — | — | 1 | 7.30 |
| CHEMBL1971172 | — | — | 1 | 7.20 |
| CHEMBL1967998 | — | — | 1 | 7.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1994669 | — | Ki | = | 3.162 | nM | 8.50 |
| CHEMBL1966628 | — | Ki | = | 3.981 | nM | 8.40 |
| CHEMBL1997554 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL1984548 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL1995813 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL1987448 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL1981047 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1980407 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1977223 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1974870 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1974870 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1084546 | PF-00562271 | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1991063 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1990885 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1990162 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1969588 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1966204 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL2007574 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1998432 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1993661 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL2006456 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1977138 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL2005478 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1985681 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL2006674 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1982271 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1996980 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1973720 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1973720 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1983923 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1965702 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1980995 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1993335 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1995712 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1967998 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1971172 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL509032 | TAE-684 | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL1979690 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL1994438 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL1967662 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL1981079 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL1987948 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL1973516 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL1973516 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL52387 | (RS)-ROSCOVITINE | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL2002649 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL1992363 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL1969151 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL422897 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL1977128 | — | Ki | = | 100.0 | nM | 7.00 |