Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1964112

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: IKBKB
ChEMBL ↗
280
Total Activities
274
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Inhibitor of nuclear factor kappa-B kinase subunit beta (CHEMBL1991) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 280 5.93 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL260092 — — 1 7.10
CHEMBL1997129 — — 1 6.80
CHEMBL590109 — — 1 6.60
CHEMBL1980995 — — 1 6.60
CHEMBL373598 — — 1 6.50
CHEMBL223367 — — 1 6.40
CHEMBL1965631 — — 1 6.40
CHEMBL413779 — — 1 6.30
CHEMBL1964687 — — 1 6.10
CHEMBL1990583 — — 1 6.10
CHEMBL1970074 — — 1 6.00
CHEMBL578061 — — 1 5.90
CHEMBL2001751 — — 1 5.90
CHEMBL1975233 — — 1 5.90
CHEMBL1991640 — — 1 5.90
CHEMBL1991180 — — 1 5.80
CHEMBL1984274 — — 1 5.80
CHEMBL363648 TAK-715 2.0 1 5.80
CHEMBL1973937 — — 1 5.80
CHEMBL2006156 — — 1 5.80
CHEMBL2002446 — — 1 5.80
CHEMBL1986263 — — 1 5.70
CHEMBL50894 ALSTERPAULLONE — 1 5.70
CHEMBL2001239 — — 1 5.70
CHEMBL2007044 — — 1 5.60
CHEMBL504950 — — 1 5.60
CHEMBL1987054 — — 1 5.60
CHEMBL583144 — — 1 5.60
CHEMBL1977223 — — 1 5.60
CHEMBL1974803 — — 1 5.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL260092 — Ki = 79.43 nM 7.10
CHEMBL1997129 — Ki = 158.49 nM 6.80
CHEMBL590109 — Ki = 251.19 nM 6.60
CHEMBL1980995 — Ki = 251.19 nM 6.60
CHEMBL373598 — Ki = 316.23 nM 6.50
CHEMBL223367 — Ki = 398.11 nM 6.40
CHEMBL1965631 — Ki = 398.11 nM 6.40
CHEMBL413779 — Ki = 501.19 nM 6.30
CHEMBL1964687 — Ki = 794.33 nM 6.10
CHEMBL1990583 — Ki = 794.33 nM 6.10
CHEMBL1970074 — Ki = 1000.0 nM 6.00
CHEMBL1991640 — Ki = 1258.93 nM 5.90
CHEMBL1975233 — Ki = 1258.93 nM 5.90
CHEMBL2001751 — Ki = 1258.93 nM 5.90
CHEMBL578061 — Ki = 1258.93 nM 5.90
CHEMBL1973937 — Ki = 1584.89 nM 5.80
CHEMBL2006156 — Ki = 1584.89 nM 5.80
CHEMBL363648 TAK-715 Ki = 1584.89 nM 5.80
CHEMBL2002446 — Ki = 1584.89 nM 5.80
CHEMBL1991180 — Ki = 1584.89 nM 5.80
CHEMBL1984274 — Ki = 1584.89 nM 5.80
CHEMBL50894 ALSTERPAULLONE Ki = 1995.26 nM 5.70
CHEMBL2001239 — Ki = 1995.26 nM 5.70
CHEMBL1986263 — Ki = 1995.26 nM 5.70
CHEMBL1977223 — Ki = 2511.89 nM 5.60
CHEMBL1987054 — Ki = 2511.89 nM 5.60
CHEMBL583144 — Ki = 2511.89 nM 5.60
CHEMBL2007044 — Ki = 2511.89 nM 5.60
CHEMBL504950 — Ki = 2511.89 nM 5.60
CHEMBL1982476 — Ki = 3162.28 nM 5.50
CHEMBL1992922 — Ki = 3162.28 nM 5.50
CHEMBL1974803 — Ki = 3162.28 nM 5.50
CHEMBL1983963 — Ki = 3162.28 nM 5.50
CHEMBL275224 NORHARMANE Ki = 7943.28 nM 5.10
CHEMBL1970083 — Ki > 3162.28 nM -
CHEMBL2007064 — Ki > 3162.28 nM -
CHEMBL2003817 — Ki > 3162.28 nM -
CHEMBL302449 GO-6976 Ki > 3162.28 nM -
CHEMBL1381197 — Ki > 3162.28 nM -
CHEMBL219722 — Ki > 3162.28 nM -
CHEMBL1964413 — Ki > 3162.28 nM -
CHEMBL1966087 — Ki > 3162.28 nM -
CHEMBL522892 DOVITINIB Ki > 3162.28 nM -
CHEMBL2000345 — Ki > 3162.28 nM -
CHEMBL1682357 — Ki > 3162.28 nM -
CHEMBL2005631 — Ki > 3162.28 nM -
CHEMBL1965988 — Ki > 3162.28 nM -
CHEMBL1964399 — Ki > 3162.28 nM -
CHEMBL1984432 — Ki > 3162.28 nM -
CHEMBL256835 — Ki > 3162.28 nM -