Compound Detail
CHEMBL1381197
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Basic Information
| ChEMBL ID | CHEMBL1381197 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WHKWRDQKKUPBMN-UHFFFAOYSA-N |
9
Targets
9
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
335.8
MW (Da)
4.06
ALogP
5
HBA
1
HBD
55.1
PSA (Ų)
0.61
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 9 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine